73 Computed Tomography Imaging to Determine Reduction in Intracrainal Pressure Before & After Posterior Vault Expansion in Apert Syndrome

Abstract Introduction Apert syndrome is an autosomal dominant malformation syndrome, accounting for 4.5% of all craniosynostoses. Raised intracranial pressure (ICP) in has a multifactorial aetiology, with incidence up to 45% if left untreated [1, 2]. ICP can be determined clinically, non-invasive and invasive methods. In this study, we want assess whether the use CT scans reliable identifying changes ICP. Method Pre postoperative 13 patients who had posterior vault expansion were assessed graded severity (ICP). The grading system used was departmental specific assessment carried out by single clinician on different brain structures. This process repeated same patients, using scans, 4 months later determine consistency repeatability. relationship between pre explored chi squared test. Intra-observer variability Kappa statistics [SS1]. Results There no statistically significant difference scan grading. Across instances, only one structure p-value <0.05. interobserver reliability test did not identify strong agreement comparison two instances data analysis. Conclusions Assessment method have expansion.